The Genome of Drosophila Melanogaster by Dan L. Lindsley

By Dan L. Lindsley

Devoted to the reminiscence of George Lefevre in reputation of his exhaustive cytogenetic research of the X chromosome, The Genome of Drosophila melanogaster is the full compendium of what's recognized in regards to the genes and chromosomes of this accepted version organism. the quantity is an updated revision of Lindsley and Grell's 1968 paintings, Genetic adaptations of Drosophila melanogaster. the recent variation includes whole descriptions of ordinary and mutant genes together with phenotypic, cytological, molecular, and bibliographic details. additionally, it describes millions of recorded chromosome rearrangements utilized in study on Drosophila. This instruction manual and its accompanying polytene chromosome maps, are sturdily sure into the e-book as foldouts and on hand as a separate set, are crucial learn instruments for the Drosophila community.

  • Describes phenotype, cytology, and molecular biology of all recorded genes of Drosophila melanogaster, plus references to the literature
  • Describes general chromosome supplement, distinct chromosome constructs, transposable components, departures from diploidy, satellite tv for pc sequences, and nonchromosomal inheritance
  • Describes all recorded chromosome rearrangements of Drosophila melanogaster as of the top of 1989 comprises the cytogenetic map of all genes as of mid-1991
  • Contains the unique polytene maps of C.B. Bridges, plus G. Lefevre's photographic equivalents, and the special maps of the chromosome fingers produced via C.B. and P.M. Bridges
  • All maps are reprinted as top of the range foldouts sturdily sure into the volume
  • Maps can also be bought individually in an eight-map packet, for laboratory and scholar use

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Additional resources for The Genome of Drosophila Melanogaster

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Discoverer: Fahmy, 1952. 29 THE GENOME OFDROSOPHILA MELANOGASTER distal 3R 210. 200 <4-CB 1 <^=17 30_ <£=A72 20_ A60 190 180 10_ ι <*-73b <#=24 <+-RM I <4-Ctx 160 150 R17 RIP 170. <4-50 <4-Wu ^=rv2 <4-LC ^=rvl9 <4-PW ^=rv3 <£=rvC8 <«-B

Sequence predicts a 50,481 dalton polypeptide with a slight negative charge; 38% amino acid homology with dopa decarboxy­ lase. Amdr: Alpha methyl dopa resistant location: 3- (between h and tn). origin: Induced by ethyl methanesulfonate. references: Bishop and Sherald, 1981, DIS 56: 21. phenotype: Based on two of 16 chromosomes selected for conferring resistance to α methyl dopa when heterozy­ gous. 10 mM for wild type. Both cytology: Placed in 19A1 based on its inclusion in Df(l)mall2 = Df(l)19Al;20F but not Df(l)malll = Df(l)19A2-3;19El or Df(l)mal3 = Df(l)19A2-3;20E-F (Tully and Gergen, 1986, J.

Nat. Acad. Sci. USA 84: 1337-39). alleles: Eight electrophoretic variants of a-amylase have been recorded; they are numbered, in order of decreasing rates of migration toward the anode, from -1 through +7 (Doane, Treat-Clemons, Gemmill. Levy, Hawley, Buchenberg, and Paigen, 1983, Isozymes: Curr. Top. Biol. Med. Res. 9: 63-70). Enzymes with mobilities 2 and 3 exist in forms with different heat sensitivities: Amy the most frequent allele, may be expressed at three different activity levels in different strains, la, lb, and lc in which la has twice the activity of lb and lb has twice the activity of lc; purified α-amylases from la and lc strains have identical specific activities (Treat-Clemmons and Doane, 1982, Isozyme Bull.

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