Textbook of medical biochemistry by MN Chatterjea, Rana Shinde.

By MN Chatterjea, Rana Shinde.

Sec. 1. phone biology --
Sec. 2. Chemistry of biomolecules --
Sec. three. Molecular biology --
Sec. four. Metabolism --
Sec. five. medical biochemistry --
Sec. 6. Miscellaneous.

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G. E. coli, A. aerogenes, and Str. lactis convert lactose of milk to lactic acid (LA) thus causing souring of milk. • Sucrose if introduced parenterally cannot be utilised, but it can change the osmotic condition of the blood and causes a flow of water from the tissues into the blood. Thus clinicians use it in oedema like cerebral oedema. If sucrose or some other disaccharides are not hydrolysed in the gut, due to deficiency of the appropriate enzyme, diarrhoea is likely to occur. 1: Differentiation of lactose from sucrose Lactose 1.

Structure: These ionophores contain hydrophilic centres that bind specific ions and are surrounded by peripheral hydrophobic regions. Types: Two types: (a) Mobile ion carriers: Like valinomycin (Refer uncouplers of oxidative phosphorylation). (b) Channel formers: Like gramicidin. 3. g. in red blood cells, and cells of the collecting ductules of the kidney, the movement of water by simple diffusion is enhanced by movements of water through water channels, composed of tetrameric transmembrane proteins called aquaporins.

Chemistry of Carbohydrates 25 has no optical activity, since the activities of each isomer cancels each other. Such a mixture is said to be Racemic. Resolution: The separation of optically active isomers from a racemic mixture is called resolution. Fig. 2: Stereoisomers of glucose As the two reacting groups aldehyde and alcoholic group belong to the same molecule, a cyclic structure takes place. If the open-chain form of D-Glucose, which may be called as Aldehydo-D-Glucose is taken, and condense the aldehyde group on carbon-1, with the alcoholic-OH group on carbon-5, two different forms of glucose are formed.

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