By A. Gorio, J.R. Perez-Polo, J. de Vellis, B. Haber
Data of all correct features of neuronal cellphone development and differentiation are provided during this quantity. rules of expression, garage and free up of nerve development components, receptor keep an eye on and the mobile responses to development elements are comprehensively mentioned. handled also are affects of varied neurotransmitters on neuronal morphogenesis and new result of interactions of cells and mediators of the immune, endocrine and worried method. designated emphasis is given to these elements regulating regeneration and nerve spreading after accidents of the nerve tissue.
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Additional info for Neural Development and Regeneration: Cellular and Molecular Aspects
BACKGROUND The neural crest is a transient embryonic structure seen at the end of neurulation during vertebrate embryogenesis. Neural crest cells originate within the neural tube, but leave the tube to migrate along characteristic pathways in the embryo, eventually giving rise to a wide variety of different cell types in the adult, including neuronal and glial cells of the peripheral nervous system, endocrine cells, pigment cells of the integument, and various connective tissue cell types in the head and neck (Le Douarin, 1982).
Acad. Sci. (USA) 76: 4913-4917. Fallon, JR (1985) Neurite guidance by non-neuronal cells in culture: Preferential outgrowth of peripheral neurites on glial as compared with no glial cell surfaces. J. Neurosci. 5: 3169-3177. ffrench-Constant, C, Miller, RH, Burne, JF & Raff, MC. Evidence that specialized type-1 astrocytes in the lamina cribrosa region of the rat optic nerve prevent the migration of oligodendrocytetype 2 (0-2A) progenitor cells into the retina. (submitted) ffrench-Constant, C. & Raff, MC (1986a) Proliferating bipotential glial progenitor cells in adult rat optic nerve.
S. areas were found to contain pigmented quail cells. 3C and 3D). 3D). 3A and 3B). The third site of localization of pigmented cells was within the germinal matrix zone in the roof of the cord (Fig. ). At all three sites, pigmented cells were spread out along the spinal cord, and not found in clusters. As before, most pigmented cells were ipsilateral to the side in which grafting occurred. 1 - Diagramatic representation compiling the locations of TPA-treated DRG cells in one chimeric embryo. 0 day chicken host, as described in the Materials and Methods.