Molecular Bioenergetics and Macromolecular Biochemistry: by Otto Wieland (auth.), Professor Dr. med. Dr. rer. nat. h. c.

By Otto Wieland (auth.), Professor Dr. med. Dr. rer. nat. h. c. Dr. med. h. c. Hans H. Weber (eds.)

The Meyerhof Symposium on "Molecular Bioenergetics and Macromolecular Biochemistry" came about in Heidelberg from the fifth to the eighth of July, 1970. The timing was once selected to coincide with the production of a brand new chair, within the Weizmann Institute of technological know-how in Rehovot, in reminiscence of OTTO MEYERHOF and the positioning was resolute through the truth that a lot of MEYERHOF'S clinical paintings used to be performed in Heidelberg. The historic reason behind the symposium was once the pressing wish of many major biochemists and physiologists lively in Molecular Biology to honour the reminiscence of 1 of the best scientists during this box and in addition one of many maximum biologists of the 20 th century. October 1971 is the 20 th anniversary of the dying of OTTO MEYERHOF and 1972 marks 50 years due to the fact he used to be presented the Nobel prize (1922). with reference to the age of a few of his neighbors and students it used to be determined the symposium to be prepared in 1970, the 1st of the 3 commemorative years.

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DEUTICKE, H. : KIin. Wochenschr. 12, 213 (1933). : Biochem. Z. 271, 89 (1934). : Biochem. Z. 286, 301 (1936). : Biochem. Z. 286, 319 (1936). : Bull. Soc. Chim. BioI. 20, 1033 (1938). : Bull. Soc. Chim. BioI. 20, 1345 (1938). FISCHER, H. O. : Ber. chem. Ges. 60, 337 (1932). : Biochem. Z. 279, 40 (1935). : BioI. Symposia 1>, 141 (1941). : Biochem. Z. 314,149 (1943). RUTTER, W. : Federation Proc. 23, 1248 (1964). TAYWR, J. , GREEN, A. , CORI, G. : J. BioI. Chem. 173, 591 (1948). ROSE, I. , RIEDER, S.

Fur unsere Fragestellung wichtiger war aber der Befund, daB auch die in der Mittelfraktion befindliche Methylsalicylsauresynthetase Pantothensaure enthielt und beide Gipfel der Pantothensaurekurve durch ein Tal getrennt sind. In der leichten Proteinfraktion im oberen Teil des Zentrifugenrohrchens wurde keine Pantothensaure gefunden, und dort war auch keine der gesuchten Enzymaktivitaten, die auf optischem Wege bei 334 nm gemessen wurden, nachzuweisen. Nach diesen Ergebllissen ist es sehr wahrscheinlich, daB das "acyl carrier protein" in Penicillium patulum nicht nur am Aufbau der Fettsauresynthetase, sondern auch an dem der Methylsalicylsauresynthetase teilnimmt.

BioI. 20, 1033 (1938). : Bull. Soc. Chim. BioI. 20, 1345 (1938). FISCHER, H. O. : Ber. chem. Ges. 60, 337 (1932). : Biochem. Z. 279, 40 (1935). : BioI. Symposia 1>, 141 (1941). : Biochem. Z. 314,149 (1943). RUTTER, W. : Federation Proc. 23, 1248 (1964). TAYWR, J. , GREEN, A. , CORI, G. : J. BioI. Chem. 173, 591 (1948). ROSE, I. , RIEDER, S. : J. Amer. Chem. Soc. 77, 5764 (1955). , TOPPER, Y. : Science 124, 982 (1956). RUTTER, W. , LING, K. : Biochim. Biophys. Acta 30,71 (1958). FISCHER, H. O. : Helv.

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