Modern concepts of focal epileptic networks by Premysl Jiruska, Marco De Curtis, John G. R. Jefferys

By Premysl Jiruska, Marco De Curtis, John G. R. Jefferys

This quantity of International evaluation of Neurobiology concentrates on glossy strategies of focal epileptic networks. the quantity addresses particular issues corresponding to seizures (including transition and termination), limbic networks, alteration of metabolism, and neocortical concentration and malformation of cortical improvement, between others.

Published due to the fact that 1959, International overview of Neurobiology is a widely known sequence beautiful to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led through an across the world popular editorial board, this significant serial publishes either eclectic volumes made of well timed stories, and thematic volumes that target fresh development in a particular quarter of neurobiology research.

      • Our wisdom in regards to the mechanisms concerned about pathophysiology of epilepsy has swiftly extended in the course of final decade
      • This unique quantity brings assessment approximately glossy innovations of epileptic concentration association and in regards to the altered neural community dynamics which ends up in propensity of the mind tissue to generate spontaneous and repeated seizures

Show description

Read or Download Modern concepts of focal epileptic networks PDF

Similar developmental biology books

Life As we Know It (Cellular Origin, Life in Extreme Habitats and Astrobiology)

Existence As we all know It covers a number of facets of lifestyles, starting from the prebiotic point, starting place of lifestyles, evolution of prokaryotes to eukaryotes and eventually to numerous affairs of people. even though lifestyles is difficult to outline, possible signify it and describe its beneficial properties. the knowledge provided the following at the numerous phenomena of existence have been all written via hugely certified authors together with scientists, a qualified athlete and 3 Nobel Laureates.

The Genome of Drosophila Melanogaster

Devoted to the reminiscence of George Lefevre in reputation of his exhaustive cytogenetic research of the X chromosome, The Genome of Drosophila melanogaster is the full compendium of what's recognized concerning the genes and chromosomes of this typical version organism. the quantity is an updated revision of Lindsley and Grell's 1968 paintings, Genetic adaptations of Drosophila melanogaster.

Advanced Microscopy in Mycology

The purpose of this quantity is to explain the most recent advances in microscopic tools, together with built-in strategies, as utilized to mycology. every one bankruptcy will supply a short review of a specific microscopic technique with linked merits and obstacles, the learn questions that may be safely addressed utilizing those microscopic tools, the way it has been effectively utilized to deal with mycological learn questions, together with helping and complimentary suggestions, and which destiny questions could be addressed.

Additional resources for Modern concepts of focal epileptic networks

Sample text

Ayala, G. F. (1987). Cellular mechanisms of epilepsy: A status report. Science, 237, 157–164. Epi K. Consortium Epilepsy Phenome/Genome P. (2013). De novo mutations in epileptic encephalopathies. Nature, 501, 217–221. , Hirsch, J. , & Bernard, C. (1997). Operative gabaergic inhibition in hippocampal ca1 pyramidal neurons in experimental epilepsy. Proceedings of the National Academy of Sciences of the United States of America, 94, 12151–12156. , & Sejnowski, T. J. (2008). Pathological effect of homeostatic synaptic scaling on network dynamics in diseases of the cortex.

Injury to the periventricular white matter due to hypoxia–ischemia, infections, or inflammation in utero or in premature infants represents the most common cause of cerebral palsy (Volpe, 2001). In the premature infant, white matter is more vulnerable than gray matter, and the period of greatest vulnerability is between GW23 and GW32. The majority of the major fiber tracts are myelinated during early childhood, but axons continue to myelinate during postnatal years. These developmental changes in myelination are identifiable by magnetic resonance (MR) images, which highlight fat (myelin) and gray matter.

A number of studies have demonstrated an imbalance between excitatory and inhibitory synaptic function. In the in utero irradiation and freeze lesion model, an impairment in GABAergic function has been reported. , 2007). 48 Heiko J. Luhmann et al. Besides a decrease in GABAergic inhibition, an increase in glutamatergic excitation has been also reported in various experimental models. , 1998) or their subunit composition may be disturbed (Hagemann, Kluska, Redecker, Luhmann, & Witte, 2003). , 2004).

Download PDF sample

Rated 4.93 of 5 – based on 35 votes