Metallopharmaceuticals II: Diagnosis and Therapy by Michael F. Tweedle, Krishan Kumar (auth.), Professor Michael

By Michael F. Tweedle, Krishan Kumar (auth.), Professor Michael J. Clarke, Professor Peter J. Sadler (eds.)

Inorganic compounds provide a lot scope for the layout of novel and healing brokers. The frequent use of paramagnetic steel complexes as powerful distinction brokers for magentic resonsance imaging (e.g. Gd) demonstrates that the toxicity of metals could be finely managed through the approriate selection of ligands. The succcessful focusing on of radioisotopes back will depend on ligand layout and steel oxidation country. Bismuth and gold complexes have lengthy been utilized in medication yet only in the near past have advances been made in figuring out the molecular foundation in their mechanism of motion. New parts with medical strength comprise using polyoxometallates and fullerenes as antiviral brokers and vanadium complexes as insulin mimetics.

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Wiener EC, Konda S, Shadron A, Brechbiel M, Gansow 0 (1997) Invest Radiol 32:748; b) Wiener EC, Patrick TA, Roy EJ, Kranz DM, Lauterbur PC (1995) Abstracts of the Soc Magn Reson Med Meeting, p 48 148. Sipkins D, Gijbels K, Tropper FD, Steinmant L, Bednarski MD, Li KCP (1995) Abstracts of the Soc Magn Reson Med Meeting, p 1139; b) Storrs RW, Tropper FD, Li HY, Song CK, Sipkins DA, Kuniyoshi JK, Bednarski MD, Strauss HW, Li KC (1995) J Magn Reson Imaging 5:719 149. Moats RA, Fraser SE, Meade TJ (1997) Angew Chern Int Ed Eng!

Inflammation, Infection and Deep-Vein Thrombosis ............. 104 104 References . . . . . . . . . . . . . . . . . . . . . . . .

Copper-62-ATSM .................................... 3 71 74 Metalloradiopharmaceuticals 47 8 Other .......... . . . . . . . . . . . . . . . . . .. 2 Pulmonary. . . . . . . . . . . . . . . . . . . . . Inflammation, Infection and Deep-Vein Thrombosis ............. 104 104 References . . . . . . . . . . . . . . . . . . . . . . . .

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