Medical Biochemistry by N.Mallikarjuna Rao

By N.Mallikarjuna Rao

This identify covers such subject matters as: biochemistry of apoptosis; biochemistry of mobile cycle; biochemistry of Bloo; organ functionality assessments; and, biochemical expertise. except updating every one bankruptcy, new unsolved difficulties are extra and in references books, reports, examine articles are integrated. hence, the 2d version of the publication includes 34 chapters, 536 references, 191 essay-type questions, 420 short-answer questions, 111 multiple-choice questions (MCQs), 128 fill within the blanks and 14 situations. such a lot extraordinary during this version is inclusion of biochemical points of illnesses and disease-causing organisms universal to tropical (developing) international locations. This identify beneficial properties: DNA structural polymorphism, DNA chips, stem cells, RAPD, peptide nucleic acids; molecular and mobile mechanisms of anxious process capabilities and illnesses; flavor and smell signalling; molecular hyperlink among weight problems and diabetes, HIV and melanoma hyperlink, immune method, human genome undertaking; lipid delivery throughout enterocytes, lipoprotein X, COX inhibitors, antiatherogenic activities of apolipo-proteins; medicinal activities of curcumin, environmental results of tobacco, mosquito repellents, damaging results of arsenic poisoning, pan masala; and, rules and functions of centrifuges to car analyzers and FMRI. The ebook is very beneficial to undergraduate clinical, dental, nursing, pharmacy, physiotherapy, homeopathy, naturopathy, biomedical engineering and scientific laboratory expertise scholars. To M.Sc. Biochemistry, lifestyles Sciences, nutrition technological know-how, foodstuff and B.Sc. Biochemistry, existence Sciences scholars additionally, this e-book turns out to be useful.

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Tyrocidin is another cyclic decapeptide. TOXIC PEPTIDES 1. Some peptides act as toxins. 2. α-amanitin is a bicyclic octapeptide present in a particular variety of mushrooms. It is extremely toxic to humans. 3. It is responsible for mushroom poisoning cases around the world. 4. When the mushrooms are consumed it causes pain in the gastrointestinal tract, vomitting, diarrhoea and nausae. 5. Death occurs within a week due of impairment of liver and kidney functions. CYCLOTIDES (CYCLIC PEPTIDES) In some peptides disulfide bonds are more.

It is a surface antibody of cells involved in anaphylactic response. The constant region of the antibody is bound to membrane receptor of leukocytes or mast cells and variable region is exposed to the outer surface. When the specific antigen reacts with antibody, it triggers the cells to release histamine and other vasoactive amines. The Ig E class also found in secretions of lungs and gut but the Ig Es lack the J chain and SC part found in Ig As and Ig Ms. Fig. 15 (a) Ig A dimer (b) Structure of Ig M (pentamer) Immunoglobulins Disorders There are numerous disorders associated with different classes of immunoglobulins.

Lipovitellin of egg Hydrophobhic Interaction 2. Glycoproteins Carbohydrates Immunoglobulins of blood, Egg albumin Covalent 3. Phosphoproteins Phosphorus Casein of milk, vitellin of egg yolk Covalent 4. 5. Nucleoproteins Hemoproteins/ Chromoproteins Nucleic acids Heme Chromatin, Ribosomes Hemoglobin, Myoglobin, Cytochromes Non-covalent Non-covalent 6. Flavoproteins Flavin nucleotides FMN, FAD Succinate Dehydrogenase Covalent 7. Metalloproteins Iron Ferritin, Cytochromes Non-covalent 8. Visual pigments Retinal Rhodopsin Covalent 3.

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