By Thaddeus Mann MD, ScD, PhD, FRS, Cecilia Lutwak-Mann MD, PhD (auth.)
To current a coherent and significant survey of medical learn endeavour in a space that has elevated as quickly as body structure and biochemistry of copy within the male is not any suggest job nowadays. No much less prodigious than the expansion of data of male reproductive functionality has been the speed at which the outpouring of courses in this topic has endured because the visual appeal of 'The Biochemistry of Semen and of the Male Reproductive Tract' in 1964. seeing that cyclopaedic therapy of this huge literature didn't entice us, we now have made no test both to rehash the cloth contained in that booklet or to amplify the bibliography past the approximately 3500 references incorporated within the current treatise. whilst, while writing, we felt strongly that to increase, it can be crucial to appreciate the earlier, and for that reason we've not hesitated to refer (especially within the introductory bankruptcy) to a few these primary early discoveries during which ultra-modern wisdom is deeply and firmly rooted.
Read or Download Male Reproductive Function and Semen: Themes and Trends in Physiology, Biochemistry and Investigative Andrology PDF
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Additional info for Male Reproductive Function and Semen: Themes and Trends in Physiology, Biochemistry and Investigative Andrology
Male insects have evolved a variety of plug-like structures, which are formed from hardened accessory secretions during copulation and completely 32 Male Reproductive Function and Semen seal off the genital region of the females. Structures of this kind, called sphragis or spermatophragma, are present in Lepidoptera, the spermatozoa of which are transferred in spermatophores. It is generally held that these plugs are placed in position not merely to stem the back flow of semen, but that they serve as a mechanical barrier against a second insemination of the female, thus providing something in the nature of a chastity belt (Parker 1970).
If capacitated rabbit spermatozoa are brought in contact with either the seminal or the epididymal plasma, they become decapacitated and lose their fertilizing ability. But removal of the seminal plasma can cause them to be de novo capacitated and thereby again rendered fertile. The decapacitation factor of the rabbit seminal plasma is a thermostable glycoprotein (mol. wt. around 350000 daltons) composed of three subunits (Eng and Oliphant 1978; Reyes et al. 1975); its relation (if any) to the large-molecular antifertility factor present in human seminal plasma remains to be explored (Reddy et al.
1978); this protein probably plays a role in the expression of vitamin A potency vis-a-vis the germinal epithelium, analogously to the protein concerned with binding of androgen. In sexually maturing males testicular vitamin A reaches its maximal concentration at a time when the spermatozoa appear; this has been convincingly demonstrated in maturing boars in which spermatogenesis becomes established around 3-8 months of age (Booth 1974). The concentration of this vitamin within the spermatozoa depends on the animal species.