Drosophila Eye Development by Kevin Moses (auth.), Dr. Kevin Moses (eds.)

By Kevin Moses (auth.), Dr. Kevin Moses (eds.)

The compound eye of Drosophila is used as a version for human affliction and homology to eyes in different taxa. This booklet covers the most important discoveries at the improvement of the compound eye of Drosophila melanogaster during the last 25 years. those contain facets of the organic mechanisms of trend formation within the anxious approach, the specification of neuronal mobilephone varieties, unforeseen phylogenetic conservation and plenty of new insights into the functionality of numerous sign transduction pathways. All chapters during this e-book were written by way of top specialists during this box who've made major contributions to our realizing of fly eye development.

Show description

Read Online or Download Drosophila Eye Development PDF

Best development books

Agricultural Trade Reform And the Doha Development Agenda (World Bank Trade and Development Series)

Agricultural exchange reform is necessary to a positive improvement consequence from the Doha improvement schedule. yet agricultural regulations and the coverage reforms being reflected are fiendishly complex, and the satan is within the information. Agricultural exchange Reform and the Doha improvement schedule builds up from the fundamental element of the price lists and different safety measures, and makes use of this data to supply an research of the big-picture implications of proposed reforms.

The Future of Foreign Aid: Development Cooperation and the New Geography of Global Poverty

The panorama of international relief is altering. New improvement actors are at the upward push, from the 'emerging' economies to varied inner most foundations and philanthropists. even as the character of the worldwide poverty 'problem' has additionally replaced: lots of the world's bad humans not dwell within the poorest international locations.

Development and Prevention of Behaviour Problems: From Genes to Social Policy

This e-book brings jointly international major researchers from different fields to discover the capability explanations of the advance of behaviour difficulties. The booklet offers theories that wish to persuade public future health, schooling and social coverage within the prevention of the expensive social issues that behaviour difficulties could cause.

Additional info for Drosophila Eye Development

Sample text

D. E. Treisman dachshund (dac; see G. Mardon, Chap. ) is not induced despite the presence of the upstream Pax-6 homologues encoded by eyeless (ey) and twin of eyeless (Quiring et al. 1994; Chen et al. 1999; Czerny et al. 1999; Curtiss and Mlodzik 2000). This may explain the requirement for dpp in initiation, as loss of Mad function at the posterior margin can be rescued by supplying eya (Curtiss and Mlodzik 2000). Ectopic dpp induces expression of eya, so and dac at the anterior eye disc margin, and ectopic ey can induce expression of these genes in other imaginal discs only when dpp is also present, confirming a critical role for dpp at this stage (Pignoni and Zipursky 1997; Halder et al.

Nature 396:272-276 Cho K-O, Chern I, Izaddoost S, Choi K-W (2000) Novel signaling from the peripodial membrane is essential for eye disc patterning in Drosophila. Cell 103:331-342 Curtiss I, Mlodzik M (2000) Morphogenetic furrow initiation and progression during eye development in Drosophila: the roles of decapentaplegic, hedgehog and eyes absent. Development 127:1325-1336 Czerny T, Halder G, Kloter U, Souabni A, Gehring WI, Busslinger M (1999) twin of eyeless, a second Pax-6 gene of Drosophila, acts upstream of eyeless in the control of eye development.

The hh homologues Sonic hedgehog (Shh) and Tiggywinkle hedgehog (twhh) are expressed in the zebrafish ganglion cell layer at the time of ganglion cell differentiation and in the adjacent retinal pigmented epithelium at the time of photoreceptor differentiation (Neumann and Niisslein-Volhard 2000; Stenkamp et al. 2000). Reduction of Shh and Twhh production by antisense oligonucleotide injection, or using null mutations in the shh gene sonic you (syu), reduces retinal ganglion cell and rod photoreceptor differentiation, while blocking all Hh family signaling with cyclopamine can prevent ganglion cell neurogenesis (Neumann and Niisslein-Volhard 2000; Stenkamp et al.

Download PDF sample

Rated 4.49 of 5 – based on 23 votes