Diagnostic Cytology by Pranab Dey

By Pranab Dey

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Attachment to the cytoskeleton and extracellular matrix. 6). Cilia are small, regular and multiple in number, whereas, flagellum is a single slender structure. Cilia are seen on the lining epithelium of the upper respiratory tract and fallopian tube. Each cilium is attached with the thick terminal plate near the apical surface of the cell. The ciliated cells are usually polar and are attached with the basement membrane. The central elongated portion of the cilium is known as axoneme. At the base of the cilium or flagellum is a basal body.

In May Grunwald Giemsa stained cytology smears, the nucleoli are stained as light-blue colored structures. 15 Nucleolus •• Subnuclear, nonmembrane bound •• Round to oval small structure, about 1 micron in diameter •• Size of the nucleolus depends upon the requirement of ribosome and protein synthesis •• Contains: Protein and rRNA •• Formation: At the end of the mitosis around the tandemly repeated clusters of ribosomal DNA genes. •• Nucleolar organizing regions: Seen in homologues chromosomes of 13, 14, 15, 21 and 22.

Gap Junctions These are intercellular channels that connect two adjacent cells. In gap junctions, the two plasma membranes are connected by the transmembrane proteins known as connexins. Function There are continuous channels between the two adjacent cells and therefore the cells can rapidly share small molecules and ions. Cell • Chapter 1 With the help of the gap junctions the action potential can rapidly travel among a group of cells without any neurotransmitter. Hemidesmosomes Hemidesmosomes connect the cell with the basal lamina.

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