By W. Sandritter (auth.), Professor Dr. K. Musshoff (eds.)
K. MUSSHOFF the crowd of illnesses often called malignant lymphomas are, for a couple of purposes, of equivalent curiosity to theoretical and scientific medication. New findings within the fields of virology and immunology might conceivably shed a few mild at the up to now unknown etiology of malignant lymphomas. A viral etiology may possibly clarify a few of the dis parate findings with any such confusing affliction as lymphogranulomatosis, which indicates either all of the symptoms of malignancy, corresponding to the attribute Reed-Sternberg and Hodgkin cells and chromosome abnormalities, and people of an inflammatory ailment, i.e. regular alterations within the blood count number and bone marrow and within the distribution of serum proteins. thus far we haven't been capable of determine the etiology of this ailment. even though, scientific observations and pathomorphological investigations regarding a joint attempt by way of various branches of drugs have introduced us toward an knowing of the scientific photograph. Descriptive anatomy has given us a transparent photo of the nearby distribution of the lymphatic approach, which has lengthy been ignored some time past. The introductory paper through Dr. S. KUBIK (Zurich), who has made beneficial contributions to our knowl fringe of the anatomy of the lymphatic approach, offers with this subject.
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Despite the number of papers, none deals in detail with the mesenchyma and parenchyma of bone marrow. In Hodgkin's disease we found characteristic lesions in the bone marrow which were completely independent of neoplastic growth. Immunological alterations must be seriously considered as a possible cause for these lesions. Studies of this kind require a sophisticated and therefore expensive technique of section preparation. Morphological studies of bone marrow slides are only of value when the nondecalcified biopsy specimen has been embedded in epoxy resin and sectioned by milling.
Reversible Leberfunktionsstorung bei Patienten mit Hypernephrom. Dtsch. med. Wschr. 96, 29 (1971). 6. LUKES, R. : Criteria for involvement of lymphnode, bone marrow, spleen, liver in Morbus Hodgkin. Cancer Res. (1972), in press. 7. : Diagnosis of Hodgkin's disease by liver biopsy. Brit. med. J. 1972 II, 1449. 8. : Unspezifische Mesenchymreaktion und Parenchymschaden der Leber bei Patienten mit Morbus Hodgkin. Dtsch. med. Wschr. 97, 323 (1972). 9. : Unspezifische Mesenchymreaktionen und Parenchymschaden der Leber bei Patienten mit Morbus Hodgkin.
50, 2368-2375 (1971). 7. : Follicular lymphoma: A special entity of malignant lymphomas. Plenary Session Papers, First Meeting of the European Division of the International Society of Haematology, Milano, pp. 108-122, ed. E. E. POLLI and A. T. MAIOLO (1971). 8. LUKES, R. : A review of the American concept of malignant lymphoma in progress in lymphology, p. 109, ed. A. RUTTIMANN. Stuttgart: Georg Thieme 1967. 9. LUKES, R. : The pathological picture of the malignant lymphomas. Proc. of the International Conference on Leukemia-Lymphoma, pp.