Diagnosis and Management of Pituitary Disorders by Andrea Lania MD, PHD (auth.), Brooke Swearingen MD, Beverly

By Andrea Lania MD, PHD (auth.), Brooke Swearingen MD, Beverly M. K. Biller MD (eds.)

This textual content offers a close replace on present diagnostic and healing options necessary within the administration of a huge spectrum of pituitary problems. The contents replicate the multidisciplinary strategy wanted for sufferers with problems of the pituitary gland, with contributions from either endocrinologists and neurosurgeons, in addition to distinctiveness contributions from radiologists, ophthalmologists, pathologists, radiation oncologists, and neurologists. The publication makes a speciality of each one pituitary tumor subtype, and comprises extra chapters regarding different lesions of the sella, together with tumor administration while pregnant and within the pediatric age group.

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The first is that knowing that a mass is a certain kind of adenoma allows consideration of specific medical treatment of the adenoma, such as dopamine agonist treatment of a lactotroph or somatotroph adenoma and somatostatin analog treatment of a somatotroph or thyrotroph adenoma. In the future there may be other possibilities as well. Even when the kind of adenoma is not one currently amenable to medical treatment, knowing that the lesion is a pituitary adenoma can influence surgical treatment.

Clinical Evaluation of Hormonal Hypersecretion by Pituitary Adenomas Patients who present with sellar masses by MRI should be evaluated by history and physical examination for evidence of hormonal hypersecretion. Even though most somatotroph adenomas cause acromegaly, sometimes the clinical features are not recognized prior to finding the adenoma as a sellar Endocrinologic Approach to Evaluation of Sellar Masses 41 mass on MRI (1). Therefore, all patients who are found to have a sellar mass should be asked about change in ring and shoe size and symptoms of sleep apnea and carpal tunnel syndrome.

Dahiya S, Sarkar C, Hedley-Whyte ET, et al. Spindle cell oncocytoma of the adenohypophysis: report of two cases. Acta Neuropathol (Berl) 2005;110:97–9. 27. Kloub O, Perry A, Tu PH, Lipper M, Lopes MB. Spindle cell oncocytoma of the adenohypophysis: report of two recurrent cases. Am J Surg Pathol 2005;29:247–53. 28. Roncaroli F, Scheithauer BW, Cenacchi G, et al. “Spindle cell oncocytoma” of the adenohypophysis: a tumor of folliculostellate cells? Am J Surg Pathol 2002;26:1048–55. 29. Lopes MB, Lanzino G, Cloft HJ, Winston DC, Vance ML, Laws ER, Jr.

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