Cellular Engineering and Cellular Therapies: Proceedings of by L. F. M. H. de Leij, M. J. A. van Luyn, M. C. Harmsen

By L. F. M. H. de Leij, M. J. A. van Luyn, M. C. Harmsen (auth.), C. Th. Smit Sibinga, L. F. M. H. De Leij (eds.)

Welcome to the town of Groningen, the heart of the North of the Netherlands. Groningen is happy with the durable culture of clinical symposia organised by way of the Sanquin Blood financial institution. those Sanquin foreign Symposia on Blood Transfusion became a real conventional occasion in Groningen, marking the early educational 12 months and feature contributed to the explicit attractiveness of Groningen and its collage within the medical box of Transfusion drugs. The growing to be culture has additionally contributed to tasks of either collage, Province and town of Groningen to carry technological know-how and jointly - BioMedCity Groningen. Such repu- tion doesn't simply occur, yet is the results of inventive and clinical management, of imaginative and prescient and an open brain, to discover in a harmony horizons. Groningen is especially happy with this attractiveness due to its management, the Sanquin Blood financial institution North-East. This yr specifically the subject matter selected a few years in the past is intensely well timed because it illustrates the actions and medical curiosity of an built-in workforce including our local Sanquin Blood financial institution North-East and matches within the urban tasks in the inspiration of BioMedCity, Groningen.

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Additional resources for Cellular Engineering and Cellular Therapies: Proceedings of the Twenty-Seventh International Symposium on Blood Transfusion, Groningen, Organized by the Sanquin Division Blood Bank North-East, Groningen

Example text

In fact like we now do it from peripheral blood, not needing any real bone marrow any more. L. de Leij: Do you mean mobilisation of adult stem cells and just take the blood. , 1. Slaper-Cortenbach (Utrecht, NL): Dr. Catherine Verfaillie described a multipotent adult progenitor cell, which she calls MAPC I . That is a cell which is able to generate all kind of different cells. But that is a cell we have to culture for over three months or so. So in order to be able to use that therapeutically it will take a long time before you have enough cells to do it anything with those cells.

Gao Z, McAlister VC, Williams GM. Repopulation of liver endothelium by bone-marrow-derived cells. Lancet 2001;357:932-33. 15. Odic D, Kajstura J, Chimenti S, et al. Bone marrow cells regenerate infarcted myocardium. Nature 2001;410:701-05. 16. Gussoni E, Soneoka Y, Strickland CD, et al. Dystrophin expression in the mdx mouse restored by stem cell transplantation. Nature 1999;401:39094. 17. Goodell MA, Rosenzweig M, Kim H, et al. Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species.

G. de Haan: Apparently this is an old idea. It is interesting to read in that paper that there was someone in the laboratory that made the suggestion to look at that. I think it is very artificial that both papers were using co-culturing experiments. So you co-culture cells, embryonic stem cells, with some adult cell and then apparently this happens. I find it very difficult to believe that occurs in vivo, that that is such a common event. I. Slaper-Cortenbach: If there is a damaged environment and stem cells are going there and than you show that there is a Y -chromosome, it does not prove anything.

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