Antioxidants in Biology and Medicine: Essentials, Advances, by Professor and Chair Dr Yunbo Li

By Professor and Chair Dr Yunbo Li

This can be a publication that takes a different method of integrating wisdom in antioxidants from necessities to advances, and from simple examine to medical purposes. This booklet offers medical info on antioxidants in an organised, cogent, and in-depth demeanour. The constant structure of writing, the full-colour illustrations, and the great checklist of references make the booklet available and interesting. in addition to its price as a textbook for undergraduate and graduate scholars in lifestyles technology, "Antioxidants in Biology and medication" may also be an invaluable reference for biomedical learn scientists, clinicians, and different well-being execs.

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Extra info for Antioxidants in Biology and Medicine: Essentials, Advances, and Clinical Applications

Sample text

However, it is important to note that in addition to their effects on ROS/RNS antioxidants, including both protein and non-protein antioxidants may also exert other biological effects irrelevant to their antioxidant activities. For example, the antioxidant enzyme catalase decomposes hydrogen peroxide to form water and molecular oxygen, a well-known antioxidant activity of catalase. 1 of Chapter 4). Another example is -tocopherol, which is known to inhibit lipid peroxidation by scavenging lipid peroxyl radical.

Biochem. J. 2009;422:313-320. [40] Muller FL, Song W, Liu Y, Chaudhuri A, Pieke-Dahl S, Strong R, et al. Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of agedependent skeletal muscle atrophy. Free Radic. Biol. Med. 2006;40:1993-2004. [41] Bivalacqua TJ, Armstrong JS, Biggerstaff J, Abdel-Mageed AB, Kadowitz PJ, Hellstrom WJ, et al. Gene transfer of extracellular SOD to the penis reduces O2-. and Superoxide Dismutase [42] [43] [44] [45] [46] [47] [48] [49] [50] [51] [52] [53] 45 improves erectile function in aged rats.

Definition and Mode of Antioxidant Action The term antioxidant is frequently used in biology and medicine, and has been defined in various ways in the literature. One common way to define this term is that antioxidant is any substance that can prevent, reduce, or repair the reactive oxygen and nitrogen species (ROS/RNS)-induced damage to a target biomolecule [1]. There are three potential modes of action by which antioxidants protect biomolecules from ROS/RNS-induced damage. They are described as follows.

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